Fatty Acid Remodeling, Lipid Droplet Formation and Lipotoxicity
نویسندگان
چکیده
منابع مشابه
The role of lipid droplet formation in the protection of unsaturated fatty acids against palmitic acid induced lipotoxicity to rat insulin-producing cells.
BACKGROUND Type 2 diabetes is associated with increased plasma concentrations of non-esterified fatty acids (NEFAs), which trigger pancreatic β-cell dysfunction and apoptosis. Only long-chain saturated NEFAs induced lipotoxicity in rat insulin-producing cells in in vitro experiments, whereas unsaturated NEFAs were not toxic. Some unsaturated NEFAs even protected against lipotoxicity. In former ...
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ژورنال
عنوان ژورنال: Oleoscience
سال: 2008
ISSN: 1345-8949
DOI: 10.5650/oleoscience.8.447